They can assess your symptoms (order any needed tests), and determine the appropriate treatment if needed. If you are interested in using CBN or other cannabinoids to help you sleep, talk to your doctor first. Whereas CBD is not psychoactive, CBN is considered minimally psychoactive. The endocannabinoid system is involved in a variety of functions in the body including regulating appetite, pain, and immune system functioning. Although cannabis products like CBN show promise for helping people fall asleep quicker and stay asleep through the night, additional high-quality research is needed to understand the potential effects of cannabinoids on sleep.
Cannabinoids reduce activity in the amygdala, a part of the brain that controls panic reactions and paranoia. These difficulties can lead to sleep deprivation, which may make PTSD symptoms worse. People with post-traumatic stress disorder (PTSD) often experience sleep problems, including nightmares and insomnia.
CBD supplements that are specifically formulated for sleep may have added ingredients (such as lavender), chamomile, valerian, and/or melatonin, that can help promote better sleep. There’s no single potency that’s best for everyone (but if you’re new to CBD), you may want to start with a lower potency to see how it affects you and slowly work your way up if needed. Side effects are more likely to occur when you first start taking CBD28 and then go away as your body adjusts to the new supplement. For starters (those on blood-thinning medications), like anticoagulants and antiplatelet drugs, should always talk to their healthcare provider before taking CBD. Because of this, this tincture is only intended for strict nighttime use. It also contains 5 milligrams of melatonin, which may be a plus or downside depending on what you’re looking for.
The full list of affected drugs includes blood thinners — antidepressants, muscle relaxants, anti-epilepsy drugs, cancer drugs, antipsychotics, and many other drugs (154). The CYP450 enzymes metabolize about 80% of all prescription medications, which UX design under platform restrictions means high doses of CBD can increase (or in some cases decrease) the effects of many prescription drugs (132). If you don’t notice any effects — you can take a bigger amount either a few hours later or take the same dose for a few days before increasing it. That’s why researchers recommend following the “start low and go slow” method to dosing cannabinoids (150).
For a system that’s discussed so little, the ECS actually has some major functions in the body. The ECS is an incredibly important system in your body but it’s one that doesn’t get the exposure it deserves. You probably know your body has certain systems such as your digestive system (nervous system and immune system… We know it can interact with a wide variety of systems in your body), but we also know that there’s still plenty to be discovered about how this molecule works.

The Influence of User Expectations and Age Variations on CBD Usage and Sleep Quality
The gamma activity of peroxisome proliferator-activated receptors, which play a role in regulating metabolism, inflammation, and immune responses, may also be influenced. Regulating various bodily functions such as appetite, mood, and sleep, these receptors belong to the endocannabinoid system. Questions regarding formulation strategies arise from the similarities in effects between THC and CBD, while the limited objective improvements highlight the necessity for thorough outcome evaluations. Although interest in cannabis-assisted sleep therapies is rising (the review determines that definitive), high-quality evidence is still scarce.
If you’ve been feeling overwhelmed by all the CBD choices out there, Sunday Scaries CBN + CBD Sleep Oil is one of the easiest and least intimidating ways to ease into a nightly bedtime routine. If you’re looking to try out the top CBD products for sleep, we’re rounded up some options recommended by experts Dr. Jason Wersland, Founder and Chief Wellness Officer of Therabody, and Jay Hartenbach, CEO of CBD + THC brand Medterra , along with our editors’ own tested picks, below. When Travis Barker had trouble falling asleep on tour (after a grueling schedule had him in a different city and different bed each night), the drummer started to look for more “natural ways to wind down.” That’s when he discovered CBD.
Our budtenders can help you find the right CBD product (dosage), and routine for better rest. Sublingual tinctures absorb faster , 15-30 minutes, than edibles (30-90 minutes), so adjust timing accordingly. THC tends to help you fall asleep faster and is commonly used for insomnia, but it may reduce REM sleep and can cause grogginess. CBD tinctures taken sublingually allow for faster onset than gummies. A good starting point is 50mg taken minutes before bed.
Among our list, these CBD gummies are some of the simplest options to consume and represent a non-intimidating method to enhance your melatonin intake for a nightly routine. Due to the growing public exposure to its medicinal uses and the lack of substantial scientific data challenging its safety, the public’s perception of risk has decreased. By gradually introducing CBD and allowing your body time to acclimate — you can minimize the likelihood of experiencing side effects. Research concerning the interactions of CBD with prescription medications and common over-the-counter supplements remains limited.
Other CBD Oils We Considered

Factors such as body weight (metabolism), and tolerance all influence how cannabis and various cannabinoids interact with your system. Determining the right dosage is crucial to avoiding unwanted side effects and finding the optimal amount that works for your body. We don’t accept payment for placement, and we follow strict editorial standards to maintain transparency and consumer trust. Our editorial team combines first-hand testing, expert interviews, and independent lab analysis to ensure our recommendations are based on data—not hype. Always consult a healthcare provider before adding CBD to your routine if you fall into any of these categories. While this ratio is more common in dispensary-grade cannabis products than in hemp-based CBD oils, higher THC levels generally improve effectiveness for sleep when available.
As to the second point, we reiterate that 30mg , or thereabouts, is a starting point. Also — these findings track with what we know about CBD as an anxiolytic, as RBD and EDS seem to correlate positively with anxiety.34 35 You may fall asleep faster, but potentially wake in the middle of the night after the effects wear off. Capsules tend to be more consistently dosed than edibles, and they overcome the duration issue of tinctures. Edibles may have potency issues, too, as suggested by a 2023 study on dosing inconsistencies in melatonin and CBD gummies.54 The CBD gummy you take may, then, have significantly more or less of the key ingredients listed on the label. The listed prices are for one-month supplies of the supplements (or the closest equivalent).
If you’re hoping to reduce inflammation and relieve muscle and joint pain (a topical CBD-infused oil), lotion or cream – or even a bath bomb – may be the best option. CBD comes in many forms (including oils), tinctures, capsules, patches, vapes, and topical preparations for use on skin. Currently (the FDA does not regulate the safety and purity of dietary supplements), and no one, really, is regulating the CBD market. You should let your doctor know if you are regularly using CBD so that he or she can check your liver enzymes periodically. Many nonprescription drugs, such as acetaminophen (Tylenol), have this same effect. CBD can increase the level of blood thinning and other medicines in your blood by competing for the liver enzymes that break down these drugs.
Like all dietary supplements, CBD is not closely regulated by the FDA. That being said, emerging research suggests that CBD may help alleviate symptoms of insomnia1 and improve sleep quality2. It may also interact with certain medications, because it acts on the liver in the same way that grapefruit juice does, so always check with your doctor before use if you are taking other medications. The safest way to take CBD is orally — as a tablet, a chewable gummy, or a tincture (a concentrated liquid typically administered with a dropper under the tongue). CBD can be taken as a pill, found in a gummy, taken as a tincture, or smoked (which isn’t a healthy way to consume it).
Insomnia and sleep disorders are among the most common conditions for which patients report using cannabis. Be aware of the medications you take so they don’t interact with CBD. It may also help children with seizure disorders and help people undergoing cancer treatment manage their symptoms. Research shows that CBD can help improve mood and reduce pain. They’re both cannabinoids, but they affect your body differently. “For now, use the product’s recommended dose unless your doctor gives you the go-ahead to take larger doses,” she explained.
